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Vol 277 No 7407 p22
1 July 2006

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Onlooker

Implications of a hazardous profession more
Many of Europe's butterflies are in danger more
Benefits of vitamin supplements queried more


Implications of a hazardous profession

A special report headed “How dangerous is chemistry?” is published in the 1 June issue of Nature. It was prompted by an explosion on 24 March at the National Institute of Higher Learning in Chemistry in the French town of Mulhouse in which a photochemist, Dominique Burget, was killed in an incident that was said to resemble an earthquake. At the same time a 19-year-old woman student working next door was severely injured. Some 400 square metres of the buildings were destroyed and rebuilding is estimated to take at least three years.

However, such serious incidents are rare in practice. This one is attributed to the spontaneous explosion of residues of ethylene stored in a pressure vessel and not connected with the experimental procedures being carried out nearby.

Chemistry, it may be argued, has been saddled with an undeserved reputation for being dangerous to study. It has been claimed that stories of accidents in laboratories tend to perpetuate out-of-date myths.

Occupational health measures from the 1970s have brought many changes. Chemicals are supplied to academic laboratories with a list of potential risks and appropriate safety precautions. Outdated practices such as eating one’s lunch at the laboratory bench, pipetting reagents by mouth and washing hands with potential carcinogens are largely no longer practised. Better analytical techniques mean that much smaller quantities of chemicals are handled and the risks from discarded wastes reduced substantially.

It is surprisingly difficult, critics say, to find national statistics regarding scientific accidents in the UK and US. Universities are required to report only accidents that result in serious health effects, although the director of health and safety at Cambridge University has commented that having a national register of accidents would be immensely useful. Most accidents on campus involve trips and falls like those in other environments.

Chemistry involves more practical work than other disciplines, with an increase in risks from broken glass, for example. It is found that academic laboratories are more dangerous than those in industry, with an accident rate 10–50 times higher. Sometimes the fact that students may work overnight in such places is a factor. Moreover, the laboratories tend to be too crowded and this, with an increased risk from spills and discarded reagents, is a major factor.

A timely comment appears in a letter published in Chemistry World for June regarding the current debate over the unpopularity of chemistry as a subject of study. The writer says that the demise of home chemistry may play a part. He, like many, was given a small chemistry set as a present in youth, which intrigued him. He widened his researches with the help of his local pharmacist, who supplied a range of chemicals and simple apparatus. All his work was done in his bedroom at home, and chemicals were exchanged with school friends.

There must be many who enjoyed the home research in their schooldays and were led to study chemistry as an academic subject as a consequence. In the era of the nanny state, simple experiments have been frowned upon despite the fact that few serious incidents occurred in the bedroom laboratories of more relaxed times. Small wonder that the numbers of professional chemists have shrunk and that university chemistry departments are struggling to survive.

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Many of Europe's butterflies are in danger

Marsh fritillaryWith the passing of the years and the changes in the earth's climate, we see fewer butterflies than we used to do. This may be a sad reflection on the human passion for trying to eliminate anything that cannot be turned into a source of money, I fear.

According to the nature conservation publications that I study regularly, there has been a marked decline in the numbers of butterflies to be encountered in the UK and in Europe in general. The change is so dramatic that several species are in danger of being wiped out. Studies since 1990 across 45 countries have revealed that of some 576 species 71 are classed as immediately threatened and many more are faced with a loss of habitat. Those restricted to only one or two habitats are seen as particularly vulnerable.

One of these species, which until recently was notable in the moorland areas of my part of the country, is the marsh fritillary, whose population there has fallen by 37 per cent during the past 25 years as a result of agricultural draining of damp fields with hedges, oak trees and willows, and also increased building in certain areas. The same habitat favoured small pearl-bordered fritillaries, purple hairstreaks and brimstones.

When wet meadows are drained and the local host plants and sources of nectar are removed, some butterflies are lost forever. Throughout Europe, butterflies in wetlands and forests were reduced during the past 25 years by 15 per cent and those in grasslands by 19 per cent.

Projects are now being organised in an effort to reverse the decline in butterfly numbers, but it will be many years before this sad state of affairs is rectified and meanwhile we shall have to accept a deteriorating situation.

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Benefits of vitamin supplements queried

In the 27 May issue of The Lancet there is a report that suggests that the widespread consumption of vitamin and mineral supplements may not have any effect in raising resistance to some chronic diseases, notably cancers, cardiovascular, endocrine, neurological, musculoskeletal, gastroenterological, renal and pulmonary diseases or age-related sensory loss. There is insufficient evidence to support or advise against commonly used supplements with some three or more vitamins and minerals without hormones, herbs or other drugs. Taking vitamins and minerals involves a potential risk and the US Food and Drug Administration is calling for more trials and increased regulation if necessary.

More than half of the adults in the US take a dietary supplement composed of vitamins and minerals, with the cost amounting to $23bn dollars a year — 65 per cent of adults take food or drinks fortified by these supplements. The European Parliament is to harmonise national rules to cover additions to foods and to inform consumers of their nutritional value. It is considered that nutrition should take a more prominent place in the medical school curriculum, such considerations being important in view of the currently escalating obesity epidemic. Not only the quantity of food but its constituents is an important aspect for consideration.

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