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PJ Online homeThe Pharmaceutical Journal
Vol 277 No 7409 p68
15 July 2006

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Children’s persistent coughs may be pertussis

Mark Clarke/Science Photo Library

Whooping cough

Whooping cough should be considered

Almost 40 per cent of school children in the UK who visit their GP with a persistent cough have evidence of whooping cough infection, even though they have been immunised, a study has revealed (BMJ Online First, 7 July 2006).

Researchers tested 172 children aged between five and 16 years with a cough lasting 14 days or longer and found that 64 (37.2 per cent) had evidence of recent pertussis.

Over 85 per cent of them had been fully immunised.

The researchers point out that while the study was being conducted the pertussis immunisation policy in the UK was changed. “Whether the most recent alteration to the UK vaccine schedule will shift the age of pertussis infections upwards without fully protecting immunised children against the disease remains to be seen,” they say.

The researchers suggest that prescribers should be alert to the possibility of a whooping cough diagnosis. “A secure diagnosis will allow GPs to give parents an indication of the likely length of cough and prevent them prescribing unnecessary drugs for asthma or referring children for further investigations.”

In response, the Health Protection Agency said in a statement: “Inactivated vaccines for bacteria usually become less effective over a period of several years. However, the vaccine protects the very youngest babies very well. It is babies less than six months old who are most at risk from dying from whooping cough and protecting them is the main purpose of the vaccination programme.”

Pneumococcal vaccine Pneumococcal vaccine is to be added to the childhood vaccination programme from September. Children up to the age of two years will be offered the vaccine when they start their routine vaccinations or as part of a catch up campaign.

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