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Vol 277 No 7411 p126
29 July 2006

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More work needed to combat C difficile infections

Dr Kari Lounatmaa/Science Photo Library

Clostridium difficile

Clostridium difficile infection on the rise

Although the incidence of methicillin-resistant Staphylococcus aureus infections in hospitals is falling, more work is needed to combat other health care associated infections, such as Clostridium difficile, the Health Protection Agency said this week.

HPA statistics show that reports of C difficile rose by 17.2 per cent in England last year from 44,107 in 2004 to 51,690 in 2005. “This increase is very likely to be due to both improved reporting and an increased number of cases,” it says.

The latest MRSA figures show that there were 3,517 cases in England reported between October 2005 and March 2006, down 2.5 per cent from the previous six months.

Health minister Andy Burnham announced this week that the Health Act gives the Secretary of State the powers to issue a code of practice for the prevention and control of health care associated infections. Trusts will have two months to implement the code, after which improvement notices may be served on those that are failing to do so.

“Some trusts have managed to reduce their rates of infection significantly, proving that it is possible to get a grip on this problem with focus and good management but elsewhere progress is not good enough and needs to improve,” said Mr Burnham.

The Healthcare Commission published its report this week on C difficile outbreaks at Stoke Mandeville Hospital, during which 334 people contracted the infection and at least 33 people died. The report highlights significant failings on the part of senior managers, who did not follow advice from infection control staff, clinicians, nurses and the HPA on stopping the spread of the infection.

Kieran Hand, lead clinical pharmacist for antimicrobials at Chelsea and Westminster Healthcare NHS Trust, London, told The Journal: “C difficile infection is associated with a number of risk factors including increasing age, prolonged hospital stay, enteral feeding, co-morbidities and, most importantly, prior antibiotic exposure. Pharmacists have an important role to play in reducing C difficile infection by discouraging indiscriminate use of broad spectrum antibiotics, ensuring that antibiotics are stopped promptly when infection has resolved or, if C difficile-associated diarrhoea (CDAD) develops, promoting effective treatment of CDAD and adhering to good infection control practice.”

Cleanyourhands campaign The National Patient Safety Agency has launched the second part of its four-year Cleanyourhands campaign this week. The campaign is designed to prompt health care staff to clean their hands immediately before and after patient contact.

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