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PJ Online homeThe Pharmaceutical Journal
Vol 277 No 7416 p267
2 September 2006

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BTS publishes cough management guidance

Steve Percival/Science Photo Library

Honey and lemon

Honey and lemon: recommended as simplest and cheapest treatment option

The first UK guidelines to provide evidence-based recommendations for the management of cough in adults are published this week as a supplement to Thorax (2006;61).

The British Thoracic Society guidelines define acute and chronic cough and review available literature in terms of clinical evaluation and management of cough.

The guidelines recommend that acute cough should be further investigated if there is evidence of haemoptysis, prominent systemic illness, suspicion of an inhaled foreign body or suspicion of lung cancer. Viral cough is almost invariably benign and prescribed treatment is regarded as unnecessary, they advise. Although patients report benefit from over-the-counter preparations there is little evidence of a specific pharmacological effect, the guidelines say. The simplest and cheapest treatment option may be a “home remedy” such as honey and lemon, they suggest.

If OTC preparations are recommended, the guidelines highlight that dextromethorphan, menthol and sedative antihistamines have demonstrated suppression of the cough reflex. Codeine and pholcodine are also antitussives but are not recommended since they have no greater efficacy than dextromethorphan and are associated with a less favourable adverse events profile.

There are no effective treatments (with an acceptable side effect profile) to control the cough response, the guidelines say. Several novel approaches, which the guidelines discuss, are currently being developed. Finally, the guidelines call for multicentre phase II trials of new drugs to be carried out at specialist cough centres, using objective measures such as cough counting.

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