Home > PJ (current issue) > News / News Centre | Search

PJ Online homeThe Pharmaceutical Journal
Vol 277 No 7424 p506
28 October 2006

This article
Reprint   Photocopy

  Acrobat Reader


News summary


NICE publishes guideline on urinary incontinence

A guideline for the management of urinary incontinence in women has been published this week by the National Institute for Health and Clinical Excellence.

The new guideline provides recommendations on the diagnosis of urinary incontinence, treatments for the condition and competencies expected of surgeons performing procedures.

In its guideline NICE recommends that duloxetine should not be used as a first-line treatment for women with stress urinary incontinence.

The guideline also says: “Duloxetine should not routinely be used as a second-line treatment for women with stress UI, although it may be offered as second-line therapy if women prefer pharmacological to surgical treatment or are not suitable for surgical treatment. If duloxetine is prescribed, women should be counselled about its adverse effects.”

The following key priorities for the conservative (non-surgical) management of the condition are offered by NICE:

· A trial of supervised pelvic floor muscle training of at least three months’ duration should be offered as first-line treatment to women with stress or mixed urinary incontinence.

· Bladder training lasting for a minimum of six weeks should be offered as first-line treatment to women with urge or mixed urinary incontinence.

· Immediate release non-proprietary oxybutynin should be offered to women with overactive bladder syndrome or mixed urinary incontinence as first-line drug treatment, if bladder training has been ineffective. If immediate release oxybutynin is not well tolerated, darifenacin [due to be launched in the UK this week], solifenacin, tolterodine, trospium or an extended release or transdermal formulation of oxybutynin should be considered as alternatives. Women should be counselled about the adverse effects of antimuscarinic drugs.

· Pelvic floor muscle training should be offered to women in their first pregnancy as a preventive strategy for urinary incontinence.

Familial breast cancer NICE has also published an update of its familial breast cancer guideline. The updated guideline recommends yearly magnetic resonance imaging screening for some women aged between 20 and 49 years if they have a high risk of breast cancer. Other recommendations on the identification and care of patients at risk of familial breast cancer remain the same.

Back to Top


©The Pharmaceutical Journal