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Vol 277 No 7426 p570
11 November 2006

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EHC: is advance supply the next step?

By Claire Anderson

Claire Anderson is professor of social pharmacy at the Centre for Pharmacy, Health and Society, University of Nottingham

Supplying emergency hormonal contraception (EHC) through community pharmacies is one pharmacy public health role that has long been campaigned for. By 2005 around 50 per cent of all EHC was supplied through community pharmacies in England — nearly double the proportion in the previous year.

The first scheme whereby pharmacists supplied EHC using collaborative prescribing agreements (similar to supplementary prescribing) started in 1997 in Washington State, US. Pharmacists in the UK, and in a number of other European countries, have been supplying EHC since 1999. UK research indicates that pharmacy supply enables most women to receive EHC within 24 hours of unprotected sexual intercourse. A recent review of international studies exploring pharmacy supply of EHC found evidence to suggest that it did not negatively impact on contraceptive use or sexual behaviour, did not increase the risk of sexually transmitted infections and was highly regarded by women who used the service. However, some women, particularly younger ones, would prefer more privacy during the EHC consultation.

Before deregulation of EHC in the UK, attitudes about potential future supply were often negative. Following the introduction of patient group directions (PGDs) and deregulation of EHC to a pharmacy medicine, most pharmacists appear to be satisfied with delivering EHC services and see them as a way to improve their role in patient-focused care. What is more they are using skills in diagnoses and prescribing. Pharmacists say that other service providers, such as family planning advisers, say that pharmacists had received better training than them. Furthermore as PGD schemes have usually been developed along with local collaborations with family planning, local GPs and organisations such as the Brook Advisory Service, this is a good example of where pharmacists have been enabled to become a valuable part of the wider health care team and are referring women to a greater range of other services.

A resounding theme of many of the studies about EHC is a fear among both pharmacists and women about the possibility of repeated use of EHC as opposed to using a regular method of contraception. Although pharmacists in the Manchester scheme had more nuanced attitudes in comparison to those uncovered by some other researchers, this may be a reflection of the multidisciplinary training received by the pharmacists. Studies indicate that women tend to overrate the health risks of emergency contraception in general and of repeated use in particular. It has also been shown that providers also tend to overestimate the potential for misuse, especially since no studies have been published that have found any empirical basis for the fear that women abuse EHC. A study tracking EHC use in 95,007 women over four years in the UK showed that 16 per cent had received EHC in the study period, and only 4 per cent had used EHC more than twice in any year. Indeed a recent European study indicates that women’s EHC experience was actually a motivating factor leading to a more consistent use of regular contraception. Moreover, abuse was not considered to be a problem for the respondents to a questionnaire in Sweden.

Part of the problem, research suggests, is undoubtedly the medical barriers imposed in many settings, such as requests for pregnancy tests and pelvic examinations. Indeed some PGD schemes in the UK have further medicalised the supply of EHC by requiring women to take their EHC tablet under supervision before leaving the pharmacy.

Another major theme of many studies about EHC is women’s and pharmacists’ concern about the effect of the availability of EHC on the incidence of STIs. A randomised controlled trial was conducted in the US comparing access to EHC through clinics (usual care), through community pharmacies and through advance supply, in which the woman received three packs of EHC. This study provides important new evidence: 2,117 women aged between 15 and 24 participated and they were followed up for six months. Pregnancy rates were similar in the three groups, as was the incidence of new STIs. There were no differences in the use of other contraceptives and no increase in risky sexual behaviour. EHC was used on more than one occasion by a small proportion of women: 6.8 per cent of women used it twice and 4.1 per cent used it three times.

The amount of information given to women during the pharmacy consultation appears to vary considerably. There is reluctance by some women to receive information about STIs and ongoing contraceptive needs as part of the EHC consultation, perhaps because they are in stable relationships and may feel that they are being judged. Some women consider their situation to be an emergency and just wish to obtain their EHC as quickly as possible. Furthermore, they might not be in the right state of mind to be receptive to receiving additional information. Other women say they did not get enough information. In considering how much information or advice to give to a woman, pharmacists are encouraged to assess each case individually.

EHC works better the quicker it is started after unprotected sexual intercourse. The success of EHC depends upon women’s ability to obtain it and pharmacy availability has been shown greatly to improve access.

It is clear from research that women with EHC on hand start therapy sooner and are more likely to use it. Randomised controlled trials in different countries have shown increased use when EHC is provided in advance. In addition a recent Scottish study shows that advance supply ensures earlier usage of EHC. Advance provision is controversial because some commentators believe it will lead to overuse, decreased use of routine contraception and sexual risk taking, as discussed above. Others have made the point that women interviewed in their study of advanced provision viewed not having to undergo the embarrassment of seeking EHC from a health professional as a positive development. However, women clearly have to access a health professional initially in order to obtain advance supplies. A commentary in The Lancet (2005;365:1668–70) asked to what extent, then, does having to contact a health professional deter younger women and those from lower socioeconomic groups from seeking EHC. It has been suggested that perhaps the easiest way of achieving continual access to EHC is for women to keep it on hand in their medicines cabinet. The Faculty of Family Planning and Reproductive Health supports the advance provision of EHC. Additionally the World Health Organization recognises that in certain circumstances it is appropriate and acceptable. The FPA has also supported it, so long as women know when and how to use it. The number of women obtaining EHC from pharmacies for future use, despite restrictions on sale and supply, is unknown. However, it would be naive to assume that, with at least 50 per cent of all EHC being supplied through pharmacies, this is not a widespread occurrence. It is time to think seriously about making emergency hormonal contraception available for advance supply from community pharmacies.

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