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Vol 277 No 7428 p630
25 November 2006

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NPSA: Improving compliance with oral methotrexate guidelines


Pharmacists should ask to see methotrexate dose booklet

Pharmacists supplying medicines to patients taking methotrexate should ask to see their blood monitoring and dosage record booklet and use it to identify potential problems, the National Patient Safety Agency's head of safety solutions has suggested.

Wendy Harris told The Journal that the NPSA would like all pharmacists to be aware of the document, which was published earlier this year (PJ, 10 June, p672). She explained that patients need to retain the document because of variations in service provision across England and Wales.

“Should any problems be identified we hope [the booklet] will inform the pharmacist’s discussion with the patient, prescriber or clinic,” she said.

Ms Harris added that the booklet is a good source of information for pharmacists to check dose changes and to confirm that the patient is attending for routine blood monitoring.

The NPSA does not expect pharmacists to issue the booklets; rather they should be given to patients by the initiating specialist when methotrexate therapy is started.

“If pharmacists identify patients who do not hold a copy of the document, then they should be communicating this matter to the prescriber or clinic and working with them perhaps to further develop local shared-care protocols and pharmacy’s role within these.”

A PDF (490K) version of the booklet is available from the NPSA website.

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