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The Pharmaceutical Journal
Vol 278 No 7436 p114
27 January 2007


Society summary

 Law and Ethics Bulletin

An occasional feature, prepared in the Royal Pharmaceutical Society’s Professional Standards Directorate, to highlight problems and inquiries currently being handled

Law and Ethics Bulletin, 2001 to present

• Methamphetamine: link to cold remedies and reclassification
• Missed doses or collections of methadone


Methamphetamine: link to cold remedies and reclassification

Methamphetamine (metamfetamine) is a highly addictive, powerful stimulant that has potentially harmful effects on the central nervous system. The drug is produced in powder, tablet or crystal form and can be snorted, smoked, swallowed or injected. Typically users experience a brief rush followed by a longer period of euphoria which lasts for a number of days.

Methamphetamine is one of the easier synthetic drugs to make, and can be produced in a few hours using everyday equipment and commonly available ingredients, including over-the-counter cold remedies. The manufacturing of methamphetamine presents a substantial risk of injury and even death from contamination, toxic gases, fire or explosion.

Use of this drug (whose street names include crystal meth, crystal, ice, burn, pure, p, crank, yaba and meth) is already extensive in North America, Australia and South East Asia. From 18 January 2007, methamphetamine has been reclassified as a Class A drug in the UK. This reflects the true harms of the drug when misused, and concerns that it is gaining a foothold in the UK illicit drugs market which could cause serious social problems.

Methamphetamine can be synthesised relatively easily from over-the-counter products containing ephedrine or pseudoephedrine. In other countries, bulk sales of certain cold remedies are closely monitored because of this risk.

Pharmacists in the UK are therefore asked to be alert to unusual requests for any items or products containing ephedrine or pseudoephedrine. In particular, requests for inappropriately large quantities of such products should be treated with caution.

Pharmacists may only supply methamphetamine to a patient on the authority of a prescription issued by an appropriate practitioner, although it is recognised that pharmacists will rarely be presented with such an authorisation. However, should any pharmacists receive such a prescription they should be aware that methamphetamine remains a Schedule 2 Controlled Drug. The product may be manufactured by a licence holder, practitioner, pharmacist or a person lawfully conducting a retail pharmacy business who is acting in their capacity as such. Requirements as to safe custody continue to apply, destruction of methamphetamine stocks must be in the presence of an authorised witness and marking of containers and the keeping of records must also be observed.


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Missed doses or collections of methadone

When providing services to drug misusers it is important to remember that several missed doses of methadone may cause a reduction in tolerance.

In the event that a patient fails to collect several consecutive days’ supplies of methadone, pharmacists must consider the patient’s best interests and whether tolerance levels may be affected and if there is a need to inform the prescriber.

In the event that a patient has not provided prior consent for their prescriber to be informed of situations where they miss one or more doses, pharmacists should explain to the patient why there is a need to inform their prescriber and attempt to seek their consent to do so. Where a patient refuses to provide consent for disclosure, pharmacists must weigh up their duty of confidentiality to the patient with the need to act in their best interests, and be prepared to justify their decision.

Pharmacists should consider the benefits of a written agreement between themselves, the patient and the prescriber or drug worker for the service to be provided, which should include the protocol to be followed when a patient does not collect their daily dose or misses a number of doses of methadone.

The Royal College of General Practitioners has issued guidance regarding supplies of methadone and the need for reassessment and re-titration if a patient consecutively misses doses (PDF 500K).

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