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PJ Online homeThe Pharmaceutical Journal
Vol 278 No 7443 p300
17 March 2007

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SMC accepts five medicines, rejects four, in latest advice

Pioglitazone (Actos) has been accepted for use within NHS Scotland to treat type 2 diabetes as part of a triple therapy regimen with metformin and a sulphonylurea.

The Scottish Medicines Consortium also accepts Suboxone (buprenorphine/naloxone) for restricted use as substitution treatment for opioid dependence.

Ivabradine (Procoralan) has been endorsed for symptomatic treatment of chronic stable angina in patients with normal sinus rhythm who do not tolerate beta-blockers and calcium-channel blockers. Exforge (amlodipine/valsartan) has been accepted for patients whose blood pressure is not adequately controlled on amlodipine or valsartan monotherapy, and parathyroid hormone (Preotact) has been recommended for the treatment of women with severe osteoporosis and at least two prior vertebral fractures.

The four drugs rejected by the SMC are glyceryl trinitrate ointment (Rectogesic) for chronic anal fissures, alglucosidase alfa (Myozyme) for Pompe disease, clostridium botulinum type A toxin (Dysport) for the treatment of focal spasticity and lidocaine plaster (Versatis) for the treatment of post-herpetic neuralgia.

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