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Vol 278 No 7446 p390
7 April 2007

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Paracetamol pack cuts had little effect on suicides

Paracetamol

Paracetamol over the counter sales were restricted in 1998

New research has shown that restricting the size of packs of paracetamol sold over the counter since 1998 might have had no effect in reducing the number of deaths from suicide.

Oliver Morgan, of the Imperial College department of primary care and social medicine, London, and colleagues analysed suicide statistics before and after the law change and found that, although paracetamol-related deaths fell, so did deaths from salicylates, antidepressants and, to a lesser extent, compound paracetamol preparations. Non-drug deaths from suicide also fell at the same rate.

They conclude that the concomitant fall in non-paracetamol deaths raises a question over whether the decline in paracetamol deaths was due to the law change or was part of a wider trend of decreasing numbers of suicides (PLoS Medicine 2007;4:e105 (PDF 170K)). “We found little evidence to support the hypothesis that the 1998 regulations limiting pack size resulted in a greater reduction in poisoning deaths involving paracetamol than occurred for other drugs or non-drug poisoning suicide,” they conclude.

Commenting on the finding in the same issue, Nicholas Buckley, from the Australian National Medical School’s department of clinical pharmacology and toxicology, Canberra, said that the research had not shown that legislation had no effect, but that it was not possible to reject the possibility that the reduction was due to chance. He added that it was likely that pack size restriction did have some effect, but that it was far more modest than had been hoped (ibid, e152 (PDF 80K)).

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