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PJ Online homeThe Pharmaceutical Journal
Vol 278 No 7449 p478
28 April 2007

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NICE launches guideline on reducing risk of VTE

Zephyr/Science Photo Library

Pulmonary embolism

Pulmonary embolism can occur as a result of deep vein thrombosis

Best practice advice on reducing the risk of venous thromboembolism (VTE) for inpatients undergoing surgery is published by the National Institute for Health and Clinical Excellence in a clinical guideline this week.

All surgical patients requiring an overnight stay should be assessed for individual risk factors for VTE (deep vein thrombosis and pulmonary embolism), it says. Patients should be offered thigh-length graduated compression stockings, unless contraindicated. Knee-length stockings can be used if thigh-length stockings are deemed inappropriate for reasons of fit or compliance, it says.

In addition to mechanical prophylaxis, patients who have risk factors for VTE, and patients having orthopaedic surgery, should be offered low molecular weight heparin, says the guideline. Fondaparinux, within its licensed indications, may be used as an alternative, it adds. This prophylaxis should be continued for four weeks after hip fracture surgery.

The guideline also specifies that health care professionals should advise patients to consider stopping combined oral contraceptive use four weeks before elective surgery and that verbal and written information about the risks of VTE and the effectiveness of prophylaxis should given to patients before surgery.

Robin Offord, director of clinical pharmacy at University College London Hospitals NHS Foundation Trust and a member of the guidance development group, believes that the guideline represents a real opportunity for pharmacists to influence best practice within their organisations.

“Most health care professionals focus their attentions on defined clinical areas, yet this guidance will impact on many different surgical specialties. Due to the diversity of their core service, pharmacy staff are ideally placed to ensure consistently high standards are achieved for patients across health care organisations, and I would expect them to be actively involved in multidisciplinary teams implementing the guidance, and evaluating its ongoing success,” he said.

The full guideline is available on the NICE website

Independent report Every hospital patient in England should have a risk assessment for venous thromboembolism, an independent expert working group has recommended.

The group’s report, launched last week by Chief Medical Officer, Liam Donaldson, says that core standards should be set by the Department of Health and compliance with these standards should be monitored by the Healthcare Commission. The report also recognises pharmacists’ role in thromboprophylaxis and recommends that a lead pharmacist for thromboprophylaxis should be identified in each trust.

The CMO has established an implementation working group to develop a national risk assessment tool.

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