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PJ Online homeThe Pharmaceutical Journal
Vol 278 No 7451 p544
12 May 2007

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Pharmacists detect more adverse drug events from drug charts than other health care workers, US study suggests

Pharmacists detect more adverse drug events (ADEs) when reviewing drug charts than other health care workers, a US study suggests (American Journal of Health-System Pharmacy 2007;64:842).

The researchers identified 13 studies that examined different health professionals’ ability to detect ADEs, including adverse drug reactions and medication errors, and which could be reasonably compared.

Their analysis showed a mean weighted ADE detection rate of 0.33 ADEs per admission for pharmacists compared with 0.16 per admission detected by non-pharmacists (doctors in all but one study, where nurses and medical record administrators were used as reviewers).

“Despite the heterogeneity, there is strong evidence that pharmacist-led interventions based on chart review report a higher ADE rate among inpatients. Our data suggest that pharmacists are the most thorough chart reviewers,” they say.

However, the researchers warn that dedicating full-time clinical pharmacist positions to ADE chart review is expensive and difficult to justify. They suggest that automation of chart review would provide a potential solution but would need to incorporate the cognitive reasoning used by pharmacists.

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