The Pharmaceutical Journal
Vol 278 No 7452 p578
19 May 2007

This article
Reprint   Photocopy

  Acrobat Reader

News summary

Preventing ulcer bleeding

Patients at high risk of ulcer bleeding and who need anti-inflammatory analgesics should receive a proton pump inhibitor and a cyclo-oxygenase-2 inhibitor, say researchers. They compared celecoxib plus esomeprazole with celecoxib alone in 273 patients. After 13 months, 12 cases of recurrent ulcer bleeding had occurred, all in patients assigned to celecoxib alone (Lancet 2007;369:1621).