Home > PJ (current issue) > News / News Centre | Search

PJ Online homeThe Pharmaceutical Journal
Vol 278 No 7453 p597
26 May 2007

This article
Reprint   Photocopy

  Acrobat Reader


News summary


NICE offers advice for secondary prevention of MI

Licensed omega-3 supplement

A licensed omega-3 supplement should be considered for some patients

All patients who have had a myocardial infarction (MI) should be offered combination treatment with an angiotensin-converting enzyme inhibitor, aspirin, a beta-blocker and a statin, new guidance from the National Institute for Health and Clinical Excellence sets out.

Published this week by the institute, “Secondary prevention in primary and secondary care for patients following a myocardial infarction” provides best-practice advice based on the latest evidence, which, the institute says, supports and updates the National Service Framework for Coronary Heart Disease. The guideline does not cover interventions made in the early stages of an acute MI.

NICE provides specific guidance on how best to implement the quadruple therapy recommended in this patient group. The guideline also sets out when it is appropriate to use warfarin, calcium channel blockers and spironolactone.

NICE also recommends that all patients are offered a cardiological assessment to consider whether coronary revascularisation is appropriate.

The guideline highlights the need for good communication between health care professionals and patients, and makes clear that patients who have had a heart attack should have the opportunity to take part in decisions about their care.

NICE is explicit in its recommendations on the consumption of omega-3 fatty acids for this patient group. The new guideline says that patients should be advised to consume at least 7g of omega-3 fatty acids each week — corresponding to two to four portions of oily fish (see Panel). NICE recommends that patients who are not achieving the suggested amount of omega-3s in their diet should be considered for supplementation (at least 1g of licensed omega-3-acid ethyl esters per day for up to four years), but only if started within three months of the MI.

Lifestyle advice

On top of drug treatment recommendations, NICE has expanded its guideline to include advice on lifestyle changes. Patients should be advised:

• To be physically active for 20 to 30 minutes a day to the point of breathlessness, starting at a level that is comfortable

• To quit smoking (if a smoker) and be offered assistance from a smoking cessation service

• To eat a Mediterranean-style diet, including more bread, fruit, vegetables and fish, and less meat

Back to Top


©The Pharmaceutical Journal