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Vol 278 No 7456 p704-705
16 June 2007

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Letters

• White Paper (2)
• Liberal professions
• Pseudoephedrine
• Substance misuse (2)
• MDS (2)
• Counterfeit medicines
• NHS
• Women in pharmacy
• Technicians (2)
• Retention fees
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Letters to the Editor

Monitored dosage systems (MDS)

Monitored dosage systems can cause more problems than they solve (Dr B. P. Curwain)

MDS not the only solution in care of the elderly (Mr P. A. Williams)

Monitored dosage systems can cause more problems than they solve

From Dr B. P. Curwain, MRPharmS

I was pleased to see Lelly Oboh’s thoughtful Broad spectrum piece (PJ, 26 May, p606) making it clear that monitored dosage systems (MDSs) are not the panacea for medicines-taking problems that some people seem to think they are. There are substantial problems of drug instability after removal from packaging and of prn medication, as well as specific issues around, for example, bisphosphonates. As a patient’s mental faculties decline, there is, in reality, a narrow period when an MDS may be helpful.

There are other ways to improve things. For many patients and their carers the provision of medication charts, such as are used in hospitals, may be most helpful. In West Hampshire, we have worked hard with social services and with care home owners to provide pharmaceutical support and training. We deliver significant training to care home staff and social services staff, and earn money for the primary care trust in so doing.

Crucially, a senior PCT medicines management pharmacist has, for a considerable time, been engaged with Hampshire social services colleagues and the result is that they now have a rewritten medicines policy. This permits care assistants to remind residents to take their medicines without requiring an MDS. The policy has been approved by social services’ lawyers and is now in place. We have also been commissioned to write materials and deliver training on medicine-taking to those who train the care assistants, and to provide ongoing support as needed to these trainers.

We are certainly not against the appropriate use of MDSs, but we are against the indiscriminate use of a tool which sometimes causes more problems than it solves.

Brian Curwain
Hampshire Primary Care Trust


MDS not the only solution in care of the elderly

From Mr P. A. Williams, MRPharmS

Further to the article by Lelly Oboh (PJ, 26 May, p606) there are a great many issues that have been associated with the provision and use of monitored dosage systems (MDSs).

I would agree that there is still great contention in terms of the funding available for MDSs. As many pharmacists and other health professionals could attest, the use of MDSs with patients has provided beneficial outcomes. Historically this is anecdotal, and the provision of an MDS is one of the many solutions that pharmacists can provide to enhance the likelihood of patients being more compliant with their treatment regimen, among other issues. Poor adherence is a growing problem given the increasing cost and the increased adverse health outcomes, including accident and emergency department visits and potential admission to hospital, if medicines are not taken.

Until fairly recently this has not been documented. I would like to point Ms Oboh, and other pharmacists involved in the provision of MDSs, to an article that was originally published online by JAMA on 13 November 2006, a report of which appeared in The Pharmaceutical Journal (18 November 2006, p597). This study is the first clinical trial specifically to address medication non-adherence in the elderly population and is one of few randomised controlled studies to demonstrate improvement in both adherence and health outcomes with the use of reminder packing (MDSs) in a comprehensive pharmacy care programme.

This study used MTS’s concordance support packaging as part of the study. The results were that the use of such a compliance device increased greatly the adherence of the patient. These patients were all selected as having more than four items of medication to take each day (a common enough occurrence in the UK).

These findings concluded that, where typically adherence rates for patients would normally decrease to 40.5 per cent at the three-month interval, and then to 32.7 per cent at six months and, thereafter, stabilise,1 with the use of an MDS as part of a pharmacy care package, adherence levels of up to 96 per cent were achieved and sustained. The study also states that “these findings are consistent with the known transient effect of medication education and imply that the continued provision of blister-packed medications was a key component of the medication adherence programme.”

I realise that the provision of MDSs is time-consuming and more costly than traditional dispensing; however we are embracing robotics and automation within the traditional dispensing role. So why not embrace automation within this aspect of pharmacy? Hopefully by doing so we can supply MDSs to patients that will increase their adherence to medication and also release much needed expertise to provide the “pharmacy care package” that we all strive to provide.

Peter Williams
Managing Director
MTS Medication Technologies

Reference

1. Chapman RH, Benner JS, Petrilla AA, Tierce JC, Collins SR, Battleman DS et al. Predictors of adherence with antihypertensive and lipid lowering therapy. Archives of Internal Medicine 2005;165:1147–52.

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