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PJ Online homeThe Pharmaceutical Journal
Vol 279 No 7472 p374
6 October 2007

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Software solutions could couple symptoms with drug side effects

Consulting SPCs can be time-consuming

Consulting SPCs can be time-consuming

Computer software could be used to discover whether a patient's reported symptoms may be linked to a side effect of their medication, according to Liverpool GP and GP trainer David Orlans.

Currently, if GPs want to check whether a patient’s symptoms may be caused by drug side effects they have to look at resources such as the British National Formulary or manufacturers’ summaries of product characteristics. “This is time consuming and information can be missed,” Dr Orlans said.

But since all patient medication is listed on the practice computer system, a computer program could search the drugs database, feed in the details of the patient’s medication and then identify any link between the recognised side effects of any medicine the patient was taking and his or her symptoms.

Dr Orlans believes that such a system could also be incorporated into programs used by pharmacies, hospital accident and emergency departments and walk-in centres and could save lives as well as millions of pounds for the NHS.

Clinical decision support provider First DataBank Europe is currently incorporating this kind of functionality into its drug knowledge base as part of ongoing development plans. Polly Shepperdson, FDBE product manager, told The Journal: “At the moment it is possible to view a list of all the side effects associated with a particular medicine. We’re gradually increasing the functionality around these data to include a search function and, later, to use coded patient symptom inputs.”

Once this functionality is made available, a clinician in any health care setting, including pharmacy, will be able to enter a symptom to find out if it, or a related symptom, is a side effect related to the patient’s list of medicines, she explained.

Dominic Vaughan, BNF publishing director, said that expanding the accessibility of BNF information is under consideration: “Using the BNF and BNF for Children side effect information in the way described is part of our road-map for digital developments.”

A system that displays appropriate BNF contra-indications information to users in real time during the prescribing process is already in use at University Hospital Birmingham NHS Foundation Trust, he pointed out. “We would expect this functionality to be delivered in a similar way,” he said.

Dr Orlans believes that a link to the Committee on Safety of Medicines should also be written into the software so that any side effects could be registered with the committee and new trends picked up.

He said: “You could get some form of post marketing surveillance on any drug anywhere in the world on a continuous basis and it would be particularly useful for new drugs.”

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