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PJ Online homeThe Pharmaceutical Journal
Vol 279 No 7474 430
20 October 2007

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Review suggests measures to halt spread of infections

Spread of epidemic respiratory viruses might be prevented by taking precautions over hygiene around younger children, a new Cochrane review concludes (Cochrane Database of Systematic Reviews 2007, issue 4).

The systematic review looks at the effectiveness of interventions that delay or reduce the spread of respiratory viruses, excluding vaccines and antiviral drugs. It identified 51 studies, including randomised controlled trials and observational studies of mixed quality.

The reviewers conclude that handwashing is an effective intervention in reducing viral spread in schools and households. They add that the effect of adding virucidals or antiseptics to normal handwashing is uncertain. In addition, six case-control studies, which assessed the impact of public health measures to contain the SARS epidemic, suggest that barrier measures, such as gloves, gowns and masks with filtration apparatus, are effective at containing epidemics.

However, the reviewers acknowledge that routine long-term implementation of some of the measures might be difficult and, without the threat of a looming epidemic, are only feasible in hospitals. They also highlight the lack of proper evaluation of global measures, such as screening at countries’ entry ports and minimising social contact.

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