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PJ Online homeThe Pharmaceutical Journal
Vol 279 No 7478 p549-556
17 November 2007

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Pages: 549   550   551   552   553   554  R&D news 555   556 

549 Pharmacists oppose transfer of global sum to PCTs Pharmacy representatives have opposed a proposal to transfer responsibility for pharmacy remuneration in England from the Department of Health to primary care trusts. NHS organisations have supported it and have indicated their desire to be more closely involved with negotiations over payment for services
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549 Government defends the electronic patient record against criticism from MPs The Government has defended the much-criticised NHS Care Records Service in its response to a House of Commons Health Committee report on the electronic patient record by saying that a number of the committee's suggestions are already being implemented
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549 Greater public understanding of NICE needed Wider discussion of the importance of assessing the cost-effectiveness of new medicines is needed to improve public understanding on this issue, according to Andrew Dillon, chief executive of the National Institute for Health and Clinical Excellence
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549 Reduction in the retention fee increase fails to quell dissent Disquiet over increases in pharmacists' retention fees for 2008 continues, in spite of the announcement of a £30 reduction in the proposed rise for practising pharmacists
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550 Extra 14p per CD for four months Pharmacy contractors in England are to get an extra 14p for each Controlled Drug prescription they dispense for four months in order to compensate them for losses caused by a change to the way prescriptions were processed by the pricing office late in 2006
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550 Minor ailment schemes need promotion, PSNC tells inquiry National standardisation and promotion of a scheme for managing minor ailments at NHS expense in community pharmacies is essential, the Pharmaceutical Services Negotiating Committee has told a Parliamentary inquiry into GP access and health improvement in primary care
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550 NPA launches pseudoephedrine/ephedrine training package Resources for pharmacists to provide awareness training for pharmacy staff on pseudoephedrine and ephedrine sales have been developed by the National Pharmacy Association
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550 PSNC investigates impact on pharmacy contract of PCT brand prescribing policies Figures are being compiled by the Pharmaceutical Services Negotiating Committee to try to find out how local primary care trust prescribing policies are distorting the nationally negotiated pharmacy contract
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551 Temporary registrants unavoidable Little could be done to address regulators' concerns that a recent European Directive on professional mobility and temporary work might undermine patient safety, the Department of Health has said
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551 UniChem to distribute Astellas immunosuppressants in UK Astellas Pharma has appointed UniChem as sole distributor for its tacrolimus products in the UK, following a spate of complaints from pharmacists unable to obtain them in a timely manner
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551 General Pharmaceutical Council As The Journal went to press there was an expectation that the first reading of the Health and Social Care Bill would take place on 15 November 2007
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551 Rimonabant psychiatric risk The anti-obesity agent rimonabant increases the risk of psychiatric adverse events, a meta-analysis of all published randomised controlled trials of the medicine suggests
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551 Drugs achieve modest weight loss On average, anti-obesity drugs achieve weight reductions of less than 5kg, a meta-analysis suggests
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552 Safety should be sole criterion for reclassification Patient safety should be the sole criterion when applications to reclassify prescription medicines as pharmacy medicines are considered, the National Pharmacy Association has told the Medicines and Healthcare products Regulatory Agency
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552 Pharmacists in Scotland should separate prescribing and dispensing Pharmacist independent prescribers in Scotland will not normally be able to dispense prescriptions they have written, according to regulations laid before the Scottish Parliament last week
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552 Peeress wants oral contraceptives to have P-medicine status Questions are to be asked in the House of Lords about making oral contraception available without prescription from community pharmacies
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552 P category considered in US Views are being sought in the US on the possibility of establishing a behind-the-counter class of medicines that can only be sold after personal intervention by a pharmacist
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552 Sexual health advice Community pharmacists can help young people understand the risks to their health from having sex with new partners abroad, the fpa has said in response to research published last week
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553 Pharmacy double victory in Scottish Health Awards Pharmacists won two of this year's Scottish Health Awards presented at a ceremony in Edinburgh last week
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554 New HIV medicine set for launch Patients with HIV who have been heavily treated with antiretrovirals may be eligible for treatment with maraviroc, a new type of medicine for HIV, available next week from Pfizer as Celsentri
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554 Technician to lead WCPPE Lesley Morgan has been appointed director of the Welsh Centre for Postgraduate Pharmaceutical Education
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R&D news

555 Prasugrel cuts CV deaths but raises bleeding risk Prasugrel is associated with fewer ischaemic events but more instances of bleeding than clopidogrel, a study of acute coronary syndromes patients scheduled to undergo percutaneous coronary intervention suggests
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555 First-in-class antidepressant prevents relapse A new type of antidepressant could help to prevent patients from relapsing. First-in-class agomelatine acts as an agonist at melatonergic MT1/MT2 receptors and as an antagonist at 5-HT2C receptors
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555 Low-dose antihypertensive drugs could be future AD therapy Valsartan has been shown to reduce one of the neurological changes known to contribute to cognitive deterioration in Alzheimer's disease (AD) in a recent animal study
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555 Another anti-TNF tested for ankylosing spondylitis and psoriatic arthritis patients Tumour necrosis factor inhibitor golimumab — being developed by Centocor and Schering-Plough — has shown promise in phase III studies of psoriatic arthritis and ankylosing spondylitis
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556 Pitrakinra study indicates potential of targeted therapy for asthma Pitrakinra, a recombinant human interleukin-4 variant, may be effective in reducing the symptoms of asthma, two phase IIa trials suggest
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556 Early results show axitinib safe in renal cancer Axitinib — a selective inhibitor of vascular endothelial growth factor receptors 1, 2 and 3 — has shown promise for people with metastatic renal-cell cancer in a phase II study, published
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556 Tezosentan fails to improve acute heart failure survival Treatment with tezosentan, an experimental medicine for acute heart failure, has failed to show improvements in symptoms or survival in a 1,435-patient trial programme
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556 Nicotine for levodopa dyskinesias Use of nicotine or selective nicotine agonists could represent a useful strategy for treating dyskinesias brought on by levodopa medicines in Parkinson's disease, according to research published online
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556 HIV vaccine not effective Merck and Co’s investigational HIV vaccine — V520 — has been shown to be ineffective at preventing HIV infection in individuals not infected with the virus at the start of a phase II study or at reducing the amount of virus within those who became infected throughout the course of the study
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556 Gastric cancer survival Combination of tegafur, gimeracil and oteracil — under investigation as “S-1” in Japan — has been shown to improve survival in a study of 529 East Asians with stage II or III gastric cancer
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556 Prucalopride for constipation Phase III research into novel 5-HT4-receptor agonist prucalopride has yielded favourable results for patients with chronic constipation
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556 Anti-cancer virus Researchers have engineered a tumour-selective poxvirus with systemic activity against cancer cells
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