The Pharmaceutical Journal
Vol 279 No 7478 p556
17 November 2007

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Nicotine for levodopa dyskinesias

Use of nicotine or selective nicotine agonists could represent a useful strategy for treating dyskinesias brought on by levodopa medicines in Parkinson's disease, according to research published online in the Annals of Neurology (24 October 2007).

Levodopa-treated monkeys with Parkinsonian-type lesions experienced fewer dyskinesias when given nicotine compared with those not receiving nicotine.