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PJ Online homeThe Pharmaceutical Journal
Vol 279 No 7482 p671
15 December 2007

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Patients link morphine with death

Cancer patients interpret the offer of morphine for pain relief as a signal that the health professional caring for them believes they are dying, a UK study suggests. This, in turn, can lead to refusal of pain relief and a reduction in patients’ quality of life.

Colette Reid, consultant in palliative medicine at Gloucester Royal Hospital and lead author of the study, said: “If we are to employ the range of available opioids in order to successfully manage pain caused by cancer, we must ensure that morphine does not remain inextricably linked with death.”

She added: “If this connection stays in place then morphine will continue to be viewed as a comfort measure for the dying rather than a means of pain control for the living.”

The researchers interviewed 18 patients with metastatic cancer to examine how they reacted when first offered an opioid drug described as similar to morphine.

The interviews revealed the importance of the role of health professionals in cancer pain management. Patients were happier to accept pain relief with an opioid if the professional showed confidence in the treatment.

The researchers suggest, too, that some patients may be frightened when offered a choice, since this indicates a lack of confidence. How beliefs about opioids are communicated to relatives may also have implications for the pain relief of others in the future, they add (Annals of Oncology 11 December 2007).

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