The Pharmaceutical Journal
Vol 279 No 7482 p673
15 December 2007

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News summary

New approach to type 2 diabetes

A range of small molecules that activate SIRT1 (an enzyme which controls pathways associated with beneficial effects on glucose homeostasis and insulin sensitivity) has been identified (Nature 2007;450:712).

The action of these molecules represents a promising new therapeutic approach for treating diseases, such as type 2 diabetes, the authors say.