The Pharmaceutical Journal
Vol 280 No 7488 p144
9 February 2008

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Nanotechnology improves implants

A nano-scale coating could help to disguise implant technologies from the body’s immune system, new research suggests (ACS Nano 2008;2:33).

Scientists have developed and tested a new drug-delivery platform that incorporates dexamethasone into a coating as thin as 4nm. Implanted into mice, discs coated with the dexamethasone-copolymer coating caused less inflammation where the disk was embedded than did uncoated disks.

The researchers believe the technique has great potential.