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PJ Online homeThe Pharmaceutical Journal
Vol 280 No 7495 p354
29 March 2008

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Epoetin delta approved for use in NHS Wales

Epoetin delta and intravenous topotecan have been recommended for use within NHS Wales, following Ministerial ratification of recommendations made at the February meeting of the All Wales Medicines Strategy Group.

Epoetin delta (Dynepo) has been recommended for the treatment of anaemia in patients with chronic renal failure. Intravenous topotecan (Hycamtin) has been approved for two indications. It is recommended for patients with relapsed small cell lung cancer for whom retreatment with the first-line regimen is not considered appropriate. It has also been approved, in combination with cisplatin, for cisplatin-naive patients with carcinoma of the cervix recurrent after radiotherapy or with stage IVB carcinoma of the cervix.

A positive recommendation by the AWMSG places an obligation on trusts and local health boards in Wales to fund treatment, but AWMSG advice is interim to any subsequent National Institute for Health and Clinical Excellence guidance.
Tacrolimus (Advagraf) was not recommended for the indications the AWMSG assessed: prophylaxis of transplant rejection in adult kidney or liver allograft recipients and treatment of allograft rejection resistant to treatment with other immunosuppressive medicines in adult patients.

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