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PJ Online homeThe Pharmaceutical Journal
Vol 280 No 7500 p529
3 May 2008

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Minimise use of heparin flushes, says NPSA

Use of heparin flush solutions in all devices should be minimised following a Rapid Response Report issued by the National Patient Safety Agency last week. The guidance is relevant to all healthcare professionals who are prescribing, dispensing or administering intravenous flush solutions to NHS patients.

Risks with heparin flushes are not well recognised by practitioners, says the NPSA, and are increased if they are not formally prescribed or subject to a patient group direction. Other problems include confusion with “look-alike” products, mis-selection for other prepared products when placed in an unlabelled syringe before administration and errors in calculating and making up dilutions.

The NPSA received 28 reports concerning mis-selection of heparin products between January 2005 and December 2007. In addition, it received eight reports where other medicines, including diamorphine, lidocaine and magnesium were selected instead of heparin.

The report notes that evidence reviewed recently by UK Medicines Information indicates that there is no advantage to using heparin flushes over normal saline for maintaining peripheral intravenous catheters. The evidence for central venous or arterial catheters is less clear and specific policies may be required locally depending on the individual devices used, it says.

The NPSA therefore recommends that:

• Organisations should review local policies to minimise the use of heparin flush solutions in all devices, including complex central venous or arterial catheters

• All flush solutions should only be administered following a prescription or patient group direction

• Local policy and procedures should be reviewed to ensure risk is minimised

• Organisations should ensure that all relevant staff are aware of this guidance and revised policies

The deadline for action to be completed is 24 July 2008. The report is available online

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