Pharmacists benefit heart failure patients
Pharmacist involvement in heart failure clinics benefits patients, according to a study reported in the latest issue of the European
Journal of Heart Failure (2005;7:405–10).
The researchers analysed the care given to 234 patients with heart failure
at specialist clinics at Barts and The London NHS Trust and Newham University
Hospital NHS Trust, London, over three years. At the clinics, treatment
is managed by pharmacists and nurses working in accordance with management
guidelines and clinical protocols that enable them to initiate and manage
drug treatments. Patients are referred to the clinics by GPs or hospital
doctors and attend on average once a month.
Most of the patients (93 of whom had moderate to severe heart failure
and 141 of whom had mild heart failure on referral to the clinic) saw
their symptoms improve.
For example, 175 patients suffered from dyspnoea when they were first
referred. Approximately one-third of these patients saw their symptoms
disappear completely after being treated at the clinic. The number of
patients with moderate or severe dyspnoea fell by about two-thirds, from
66 to 23. Similarly, 158 patients experienced fatigue when they were
first referred. After treatment, this fell to 138 while the number of
patients with moderate or severe symptoms fell by almost a quarter from
55 to 44.
Some patients saw their condition (and not just their symptoms) improve
significantly following treatment. Almost half of those diagnosed with
moderate or severe heart failure after referral were reassessed later
and diagnosed with mild heart failure.
A positive impact on patients’ lifestyle was also reported. A total
of 44 patients were regular smokers when they were first referred. Half
of these went on to give up. Seven patients drank more than the recommended
weekly intake of alcohol when they were first assessed. This fell to
just one after treatment at the clinic.
Pharmacist involvement also led to more patients receiving optimum drug
therapy. For example, almost two-thirds of patients (143) were not receiving
all the drugs (ie, angiotensin converting enzyme [ACE]-inhibitors, beta-blockers
and spironolactone) they needed on referral. This was reduced to 50 following
treatment, with most of those not receiving these drugs being either
intolerant of them or having contra-indications. Similarly, the number
of patients receiving “medium” or “high” doses
(appropriate in the circumstances) rose from 43 to 134 for beta-blockers,
from 107 to 153 for ACE-inhibitors and from 129 to 201 for angiotensin
receptor blockers.
Valerie Ross, specialist heart failure pharmacist at Barts and The London
NHS Trust, said: “The specialist pharmacists and nurses who staff
these clinics work with doctors to ensure patients receive the right
medication at the right doses. They can also offer advice to patients
to encourage them to give up smoking, cut down on the amount of alcohol
they drink and improve their overall health. The results from this study
show the clinics are benefiting patients.”
Stem cells and heart failure at Barts and the London
A trial will shortly be launched at Barts and
The London NHS Trust to find out if a patient’s own stem cells can be used to treat
heart failure. This is believed to be the UK’s first large-scale
patient trial of its type. The trust has teamed up with the Heart
Cells Foundation to raise the £6m needed to fund the trial,
which will involve 600 patients and will run for five years. |
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