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2007;14:322
November 2007

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Flu vaccination in the elderly does not reduce hospital cases

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Flu vaccination

Flu vaccination alone will not reduce pressure on hospital beds over the winter

Influenza vaccination should not be the sole tactic for reducing hospital admissions of elderly patients over the winter months, according to a group of UK researchers.

A case-control study examining the effect of flu vaccination on preventing hospital admissions in the elderly between October 2003 and March 2004 found that routine flu vaccination did not reduce hospital admissions.

Cases were defined as patients who presented to their GP with acute respiratory illness and were consequently admitted to hospital. Controls were recruited from the patients who presented to their GP but were treated in the community.

Of the 157 cases, 74.5 per cent had received a flu vaccination at least three weeks before they presented to the GP, compared with 74.2 per cent of the 639 controls. After adjustment for factors such as age, sex and smoking status, this gave an odds ratio of 1.2 (95 per cent confidence interval 0.8–1.9).

A benefit was observed when analysis was restricted to the weeks of peak virus activity (9 November to 9 December), although it was not statistically significant.

However, the researchers cautioned against interpreting their results to suggest that flu vaccination was futile, because other benefits of vaccination (eg, reducing infection, morbidity and mortality) had not been assessed.

They say that rather than relying on flu vaccination to reduce winter bed pressures, attention should be given to other factors such as treatment of comorbidities and housing conditions.

The study was published online in Vaccine on 21 September 2007.

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