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PJ Online homeHospital Pharmacist
2007;14:362
December 2007

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E-prescribing system reduces drug errors

Electronic prescribing in paediatrics reduces adverse drug events (ADEs), say US researchers.

They compared the number of ADEs that occurred during approximately 1,200 paediatric hospital admissions, before and after the installation of an electronic prescribing system. An ADE was defined as an injury caused by receiving a drug or not receiving an intended drug.

Also defined were potential ADEs (a “near miss” for an error that would result in “at least significant” injury) and preventable ADEs (an ADE due to a medication error).

The results show a significant reduction in total ADEs, preventable ADEs and potential ADEs. A total of 76 ADEs (of which 46 were preventable) and 94 potential ADEs occurred before electronic prescribing was installed, compared to 37, 26 and 35 after installation, respectively. This means that one potential ADE was avoided for every 20.2 admissions and one preventable ADE was avoided for every 59.0 admissions.

The system was most effective at reducing errors associated with aminoglycosides (a reduction from 12 to 0) and cephalosporins (a reduction from 14 to two). However, the system did not reduce the number of occasions when inadequate analgesia (a preventable ADE) was prescribed.

The authors conclude that using electronic prescribing with substantial decision support reduces actual and potential drug errors. However, further system refinements are required to prevent the remaining ADEs (Paediatrics 2007;120:1058–66).

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