Landmark drugs

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Ciprofloxacin

Inderal

Propofol

Prozac

Tagamet

Ventolin

Zidovudine

(1) Ventolin remains a breath of fresh air for asthma sufferers, after 40 years
In the first article in a series on landmark drugs, Jenny Bryan retells the history of Ventolin and explains why it still plays a major role in the treatment of asthma
(PDF 100K)

Pharmaceutical Journal, 2007; 279; 404-405 (13 October 2007)

(2) Inderal — a forerunner of a radically new generation of products
In the second article in a series on landmark drugs, Jenny Bryan discusses the development of Inderal (propranolol) and beta-blockers, and looks at how Inderal was a major advancement in the treatment of hypertension and why it has slowly been superseded by other, newer agents
(PDF 60K)

Pharmaceutical Journal, 2007; 279; 538-539 (10 November 2007)

(3) No longer a pain in the gut — how Tagamet led peptic ulcer treatments
In the third article in a series on landmark drugs, Jenny Bryan retells the dramatic effect that Tagamet had on millions of peptic ulcer sufferers
(PDF 100K)

Pharmaceutical Journal, 2007; 279; 656-657 (8 December 2007)

(4) Prozac — is it worthy of the hype?
In the fourth article in a series on landmark drugs, John Donoghue takes a look at Prozac and the massive media attention it has received over the years. Has Prozac delivered what it promised?
(PDF 50K)

Pharmaceutical Journal, 2008; 280; 57-58 (19 January 2008)

(5) Ciprofloxacin — not invincible
In the fifth article in a series on landmark drugs, Jenny Bryan looks at the antibiotic ciprofloxacin, initially seen as a “quantum-leap” forward and the answer to antibacterial resistance, but subsequently found not to be as invincible as people thought
(PDF 80K)

Pharmaceutical Journal, 2008; 280; 187-188 (16 February 2008)

(6) Zidovudine — a harbinger of hope for sufferers from AIDS in the 1980s
In this sixth article in a series on landmark drugs, Jenny Bryan looks at the antiviral zidovudine, which, as the first drug to be licensed for the treatment of AIDS, brought hope to sufferers, who at the time were mainly gay men, and saved them from an automatic death sentence
(PDF 60K)

Pharmaceutical Journal, 2008; 280; 309-310 (15 March 2008)

(7) Propofol has withstood the test of 20 years at the forefront of anaesthesia
In the seventh article in a series on landmark drugs, Jenny Bryan looks at propofol, an intravenous anaesthetic that remains in mainstream use
(PDF 50K)

Pharmaceutical Journal, 2008; 280; 482-483 (19 April 2008)

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