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(1) Back to basics: pharmacokinetics
(PDF
180K)
In the first article in a series intended to remind pharmacists
about the basic principles of pharmacokinetics, pharmacodynamics
and therapeutic drug monitoring, Alison Thomson describes the
principal pharmacokinetic parameters
Pharmaceutical Journal, 19 June 2004, 769-771. Vol 272, no
7304
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(2) Variability in drug dosage requirements
(PDF 65K)
In the second article in a series intended to remind pharmacists about the basic
principles of pharmacokinetics, pharmacodynamics and therapeutic drug monitoring,
Alison Thomson describes inter-individual variability issues that should be considered
when recommending a dosage regimen
Pharmaceutical Journal, 26 June 2004, 806-808. Vol 272, no 7305
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(3) Why do therapeutic drug monitoring
(PDF 150K)
In this third article in our back to basics series on pharmacokinetics, Alison
Thomson gives an overview of the factors that make therapeutic drug monitoring
necessary and looks at some of the groups of drugs where monitoring is often
needed
Pharmaceutical Journal, 31 July 2004, 153-155. Vol 273, no 7310
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(4) Examples of dosage regimen design
(PDF 200K)
In this final article in our back to basics series on pharmacokinetics, Alison Thomson uses two case studies to describe approaches that can be taken to design drug dosage regimens to achieve target concentrations in individual patients
NOTE The answers to the practice point questions are at the end of the PDF
file
Pharmaceutical Journal, 7 August 2004, 188-190. Vol 273, no 7311
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